1Sherr CJ, Roberts JM. Living with or without cyclins and cyclin-dependent kinases. Genes Dev. 2004;18:2699-2711. http://dx.doi.org/10.1101/gad.1256504
2Barrière C, Santamaría D, Cerqueira A, et al. Mice thrive without Cdk4 and Cdk2. Mol Oncol. 2007;1(1):72-83. http://dx.doi.org/10.1016/j.molonc.2007.03.001
3Thibault S, Hu W, Hirakawa B, et al. Intestinal toxicity in rats following administration of CDK4/6 inhibitors is independent of primary pharmacology. Mol Cancer Ther. 2019;18(2):257-266. http://dx.doi.org/10.1158/1535-7163.MCT-18-0734
4Data on file, Eli Lilly and Company and/or one of its subsidiaries.
5Slavin RE, Dias MA, Saral R. Cytosine arabinoside induced gastrointestinal toxic alterations in sequential chemotherapeutic protocols: a clinical-pathologic study of 33 patients. Cancer. 1978;42(4):1747-1759. https://doi.org/10.1002/1097-0142(197810)42:4<1747::aid-cncr2820420413>3.0.CO;2-T1747::aid-cncr2820420413>
6Khan SA, Wingard JR. Infection and mucosal injury in cancer treatment. J Natl Cancer Inst Monogr. 2001;2001(29):31-36. https://doi.org/10.1093/oxfordjournals.jncimonographs.a003437
7Boussios S, Pentheroudakis G, Katsanos K, Pavlidis N. Systemic treatment-induced gastrointestinal toxicity: incidence, clinical presentation and management. Ann Gastroenterol. 2012;25(2):106-118. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959393/
8Stacey R, Green JT. Radiation-induced small bowel disease: latest developments and clinical guidance. Ther Adv Chronic Dis. 2014;5(1):15-29. https://doi.org/10.1177/2040622313510730